With an expanding subsea energy sector demanding more complex subsea structures with increased lifetimes, traditional tools and guidelines for designing cathodic protection systems are becoming less effective. This creates a need to develop new methodologies that ensure adequate cathodic protection of subsea structures, mitigating complex subsea environmental risks. Leveraging our expertise in computational modelling and simulation capabilities, OneSubsea is reimagining the design of cathodic protection systems. Where industry-standard methodologies provide only a rough estimate of the total anode mass required, simulation-based methodologies allow for optimization of the total anode mass and its spatial distribution. This approach reduces operational costs through digitalization and automation, ensuring sufficient protection while mitigating risks associated with overprotection such as hydrogen-induced stress cracking and calcareous deposit buildup. The new methodology employs case-specific polarization curves imitating the subsea conditions for the materials of interest to ensure accurate results. As such, complex physics is captured and converted to a data set used as simulation input. The method has been validated through laboratory experiments. The validation work concluded that the model produced highly accurate results for all cases tested. Additionally, the validation process provided valuable insights into the creation of polarization curves. With the model validated, the framework has been expanded to capture the continuous consumption of anodes over time. This provides valuable insights into the performance of cathodic protection systems throughout the lifecycle of subsea structures, supporting predictive maintenance and real-time monitoring technologies.